{"request_comments":[{"id":639,"text":"I see in the responses to other questions below the discovery of new preservatives is of interest, however the TRL scale indicates experimental results are the earliest point to engage. Can you please clarify? ","approved":true,"created_at":"2024-02-05T16:35:57.075-05:00","updated_at":"2024-07-07T17:22:31.177-04:00","cached_votes_up":4,"cached_votes_down":0,"request_id":617,"open":true,"replies":[{"id":668,"text":"Hi Jasmin, \nThank you for your question. We are looking for commercially-available/fully scaled-up preservatives as well as discover new preservatives that have the potential to scale up. As long as we can see a potential for scale up for experimental results in preservative discovery projects we are interested. I hope this answers your question, if you need any further clarification please feel free to reach out anytime.\nThanks,\nAiswariya.","approved":true,"created_at":"2024-02-15T10:53:24.217-05:00","updated_at":"2024-02-15T10:53:24.217-05:00","cached_votes_up":0,"cached_votes_down":0,"request_id":617,"open":true,"reply_to":{"id":639,"text":"I see in the responses to other questions below the discovery of new preservatives is of interest, however the TRL scale indicates experimental results are the earliest point to engage. Can you please clarify? ","approved":true,"created_at":"2024-02-05T16:35:57.075-05:00","updated_at":"2024-07-07T17:22:31.177-04:00","cached_votes_up":4,"cached_votes_down":0,"request_id":617,"open":true,"user":{"id":145193,"name":"Jasmin Hume","role":0,"image":{"url":null,"big":{"url":null},"medium":{"url":null},"small":{"url":null}},"profile_id":"jasmin-hume-145193","profile_info":{"id":141143,"user_id":145193,"startup_id":null,"university_id":null,"university_start_year":null,"university_end_year":null,"title":"CEO","headline":null,"about":null,"research_areas":null,"updated_at":"2024-02-05T15:57:58.256-05:00","location":"Shiru Inc.","startup":{"id":3269,"url":null,"startup_name":"Shiru Inc.","start_year":null,"end_year":null,"primary_affiliation":true,"title":"CEO"},"educations":[],"user_organization_histories":[{"id":9354,"organization_type":"Company","organization_id":3269,"user_id":145193,"start_year":null,"end_year":null,"title":"CEO","verified":false,"primary_affiliation":true,"created_at":"2025-11-18T05:01:06.489-05:00","updated_at":"2026-02-04T12:18:14.363-05:00","organization":{"id":3269,"company_name":"Shiru Inc.","url":null,"name":"Shiru Inc."}}],"is_university_scientist":false,"is_startup_scientist":true,"proposals":[]}}},"replies":[],"user":{"id":134958,"name":"Aiswariya Deliephan","role":1,"image":{"url":"https://cdn.halo.science/uploads/users/134958/Aiswariya_Deliephan.jpg","big":{"url":"https://cdn.halo.science/uploads/users/134958/big_Aiswariya_Deliephan.jpg"},"medium":{"url":"https://cdn.halo.science/uploads/users/134958/medium_Aiswariya_Deliephan.jpg"},"small":{"url":"https://cdn.halo.science/uploads/users/134958/small_Aiswariya_Deliephan.jpg"}},"profile_id":"aiswariya-deliephan-134958","profile_info":{"id":1555,"user_id":134958,"company_id":1961,"verified":true,"title":"Senior Scientist","role":"Subject Matter Expert","commenter":false,"license":"premium","company_identifier":"kraft-heinz","company_name":"Kraft Heinz","is_admin":false,"is_super_admin":false}}}],"user":{"id":145193,"name":"Jasmin Hume","role":0,"image":{"url":null,"big":{"url":null},"medium":{"url":null},"small":{"url":null}},"profile_id":"jasmin-hume-145193","profile_info":{"id":141143,"user_id":145193,"startup_id":null,"university_id":null,"university_start_year":null,"university_end_year":null,"title":"CEO","headline":null,"about":null,"research_areas":null,"updated_at":"2024-02-05T15:57:58.256-05:00","location":"Shiru Inc.","startup":{"id":3269,"url":null,"startup_name":"Shiru Inc.","start_year":null,"end_year":null,"primary_affiliation":true,"title":"CEO"},"educations":[],"user_organization_histories":[{"id":9354,"organization_type":"Company","organization_id":3269,"user_id":145193,"start_year":null,"end_year":null,"title":"CEO","verified":false,"primary_affiliation":true,"created_at":"2025-11-18T05:01:06.489-05:00","updated_at":"2026-02-04T12:18:14.363-05:00","organization":{"id":3269,"company_name":"Shiru Inc.","url":null,"name":"Shiru Inc."}}],"is_university_scientist":false,"is_startup_scientist":true,"proposals":[]}}},{"id":592,"text":"Are SME's / companies eligible for this RFP? Or just academic researchers?","approved":true,"created_at":"2024-01-11T06:50:40.759-05:00","updated_at":"2024-01-16T05:46:10.529-05:00","cached_votes_up":1,"cached_votes_down":0,"request_id":617,"open":true,"replies":[{"id":612,"text":"Hi Joshua,\nThanks for reaching out. SME's/companies as well as academic researchers are all eligible for this RFP.\nRegards,\nAiswariya.","approved":true,"created_at":"2024-01-17T14:33:36.417-05:00","updated_at":"2024-01-17T14:33:43.981-05:00","cached_votes_up":0,"cached_votes_down":0,"request_id":617,"open":true,"reply_to":{"id":592,"text":"Are SME's / companies eligible for this RFP? Or just academic researchers?","approved":true,"created_at":"2024-01-11T06:50:40.759-05:00","updated_at":"2024-01-16T05:46:10.529-05:00","cached_votes_up":1,"cached_votes_down":0,"request_id":617,"open":true,"user":{"id":140446,"name":"Joshua Yeres","role":0,"image":{"url":null,"big":{"url":null},"medium":{"url":null},"small":{"url":null}},"profile_id":"joshua-yeres-140446","profile_info":{"id":136494,"user_id":140446,"startup_id":null,"university_id":null,"university_start_year":null,"university_end_year":null,"title":"Business Development","headline":null,"about":null,"research_areas":null,"updated_at":"2024-01-11T06:49:00.161-05:00","location":"Ascola Economic and Financial Consulting Ltd","startup":{"id":8111,"url":"https://idea-re.net/","startup_name":"Ascola Economic and Financial Consulting Ltd","start_year":null,"end_year":null,"primary_affiliation":true,"title":"Business Development"},"educations":[],"user_organization_histories":[{"id":9288,"organization_type":"Company","organization_id":8111,"user_id":140446,"start_year":null,"end_year":null,"title":"Business Development","verified":false,"primary_affiliation":true,"created_at":"2025-11-18T05:01:04.467-05:00","updated_at":"2025-11-25T07:08:48.803-05:00","organization":{"id":8111,"company_name":"Ascola Economic and Financial Consulting Ltd","url":"https://idea-re.net/","name":"Ascola Economic and Financial Consulting Ltd"}}],"is_university_scientist":false,"is_startup_scientist":true,"proposals":[]}}},"replies":[],"user":{"id":134958,"name":"Aiswariya Deliephan","role":1,"image":{"url":"https://cdn.halo.science/uploads/users/134958/Aiswariya_Deliephan.jpg","big":{"url":"https://cdn.halo.science/uploads/users/134958/big_Aiswariya_Deliephan.jpg"},"medium":{"url":"https://cdn.halo.science/uploads/users/134958/medium_Aiswariya_Deliephan.jpg"},"small":{"url":"https://cdn.halo.science/uploads/users/134958/small_Aiswariya_Deliephan.jpg"}},"profile_id":"aiswariya-deliephan-134958","profile_info":{"id":1555,"user_id":134958,"company_id":1961,"verified":true,"title":"Senior Scientist","role":"Subject Matter Expert","commenter":false,"license":"premium","company_identifier":"kraft-heinz","company_name":"Kraft Heinz","is_admin":false,"is_super_admin":false}}}],"user":{"id":140446,"name":"Joshua Yeres","role":0,"image":{"url":null,"big":{"url":null},"medium":{"url":null},"small":{"url":null}},"profile_id":"joshua-yeres-140446","profile_info":{"id":136494,"user_id":140446,"startup_id":null,"university_id":null,"university_start_year":null,"university_end_year":null,"title":"Business Development","headline":null,"about":null,"research_areas":null,"updated_at":"2024-01-11T06:49:00.161-05:00","location":"Ascola Economic and Financial Consulting Ltd","startup":{"id":8111,"url":"https://idea-re.net/","startup_name":"Ascola Economic and Financial Consulting Ltd","start_year":null,"end_year":null,"primary_affiliation":true,"title":"Business Development"},"educations":[],"user_organization_histories":[{"id":9288,"organization_type":"Company","organization_id":8111,"user_id":140446,"start_year":null,"end_year":null,"title":"Business Development","verified":false,"primary_affiliation":true,"created_at":"2025-11-18T05:01:04.467-05:00","updated_at":"2025-11-25T07:08:48.803-05:00","organization":{"id":8111,"company_name":"Ascola Economic and Financial Consulting Ltd","url":"https://idea-re.net/","name":"Ascola Economic and Financial Consulting Ltd"}}],"is_university_scientist":false,"is_startup_scientist":true,"proposals":[]}}},{"id":645,"text":"Live cultures that have antifungal/anti-yeast activity. Are bacteria with strong antifungal properties (volatiles or metabolites) of interest for further identification of compounds and potential for application?","approved":true,"created_at":"2024-02-08T07:39:05.778-05:00","updated_at":"2024-02-08T08:56:07.944-05:00","cached_votes_up":1,"cached_votes_down":0,"request_id":617,"open":true,"replies":[{"id":667,"text":"Hi Bart,\nThank you for your question. Yes, absolutely - bacterial metabolites or volatiles are of interest for potential application as antimicrobials.\n","approved":true,"created_at":"2024-02-15T10:46:57.241-05:00","updated_at":"2024-02-15T10:46:57.241-05:00","cached_votes_up":0,"cached_votes_down":0,"request_id":617,"open":true,"reply_to":{"id":645,"text":"Live cultures that have antifungal/anti-yeast activity. Are bacteria with strong antifungal properties (volatiles or metabolites) of interest for further identification of compounds and potential for application?","approved":true,"created_at":"2024-02-08T07:39:05.778-05:00","updated_at":"2024-02-08T08:56:07.944-05:00","cached_votes_up":1,"cached_votes_down":0,"request_id":617,"open":true,"user":{"id":145209,"name":"Bart Fraaije","role":0,"image":{"url":null,"big":{"url":null},"medium":{"url":null},"small":{"url":null}},"profile_id":"bart-fraaije-145209","profile_info":{"id":141154,"user_id":145209,"startup_id":null,"university_id":5926,"university_start_year":null,"university_end_year":null,"title":"Principal Investigator","headline":"Plant pathology, fungal diagnostics, resistance management","about":"Works on fungal plant pathogens, developing PCR-based diagnostics, tracking resistance evolution, and informing fungicide stewardship. 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Or are you willing to work with a commercially available preservatives? And do you have a specific product in mind as well?\r\n\r\nAnn ","approved":true,"created_at":"2024-01-05T18:24:47.036-05:00","updated_at":"2024-01-07T13:57:48.987-05:00","cached_votes_up":1,"cached_votes_down":0,"request_id":617,"open":true,"replies":[{"id":585,"text":"Hi Ann,\nThank you for your questions. We are looking for commercially available preservatives as well as discover new preservatives that have the potential to scale up. Currently we do not have any specific product in mind; we prefer the technologies/categories mentioned under 'solutions of interest' in the proposal.\n\nAiswariya.","approved":true,"created_at":"2024-01-09T12:07:18.086-05:00","updated_at":"2024-01-09T12:07:18.086-05:00","cached_votes_up":0,"cached_votes_down":0,"request_id":617,"open":true,"reply_to":{"id":575,"text":"Hello Kraft/Heinz Team, \r\nAre you looking for us to discover a new preservatives? Or are you willing to work with a commercially available preservatives? And do you have a specific product in mind as well?\r\n\r\nAnn ","approved":true,"created_at":"2024-01-05T18:24:47.036-05:00","updated_at":"2024-01-07T13:57:48.987-05:00","cached_votes_up":1,"cached_votes_down":0,"request_id":617,"open":true,"user":{"id":140379,"name":"Ann Vegdahl","role":0,"image":{"url":null,"big":{"url":null},"medium":{"url":null},"small":{"url":null}},"profile_id":"ann-vegdahl-140379","profile_info":{"id":136443,"user_id":140379,"startup_id":null,"university_id":1013,"university_start_year":null,"university_end_year":null,"title":"Research Associate","headline":"Food Microbiology, Preservation, and Safety","about":"Ann Vegdahl studies microbial stability of foods, with emphasis on shelf-stable and low/nonalcoholic beverages. 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The requested technology readiness levels are 3-9 i.e. experimental proof of concept (number 3) at the minimum, up to product in market (number 9). TRL-3 means that we prefer some experimental evidence to support the antimicrobial/antifungal efficacy of the proposed ingredient. I hope this answers your question.\nRegards,\nAiswariya.","approved":true,"created_at":"2024-02-27T14:50:46.785-05:00","updated_at":"2024-02-27T14:50:46.785-05:00","cached_votes_up":0,"cached_votes_down":0,"request_id":617,"open":true,"reply_to":{"id":705,"text":"Could you please explain more about the expectation for the level of detail for proposals based on the \"basic principles observed\" and the \"concept development\", which are the requested technology readiness levels?","approved":true,"created_at":"2024-02-25T14:55:28.132-05:00","updated_at":"2024-02-25T16:04:52.868-05:00","cached_votes_up":1,"cached_votes_down":0,"request_id":617,"open":true,"user":{"id":7793,"name":"Gloria Muday","role":0,"image":{"url":null,"big":{"url":null},"medium":{"url":null},"small":{"url":null}},"profile_id":"gloria-muday-7793","profile_info":{"id":7821,"user_id":7793,"startup_id":null,"university_id":1169,"university_start_year":"1991","university_end_year":"Present","title":"Principal Investigator","headline":"Crop Reproduction, Heat Stress, Redox Signaling","about":"Research focuses on how reactive oxygen species and hormone networks govern pollen performance and root/stomatal function under stress. 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Is that enough work done to submit to this rfp?","approved":true,"created_at":"2024-02-24T14:24:39.292-05:00","updated_at":"2024-02-25T16:04:18.161-05:00","cached_votes_up":1,"cached_votes_down":0,"request_id":617,"open":true,"replies":[{"id":716,"text":"Hi Bruce, \nThank you for checking with us. Have the bacterial strains been tested on a lab scale against any spoilage yeasts or molds? We are primarily interested in food spoilage yeasts and molds, including acid tolerant yeasts. We would prefer some evidence in the RFP, preferably lab scale antimicrobial assays or if not, other literature evidence supporting that the bacterial strains have antifungal/antimicrobial effect against food spoilage molds and/or yeasts.\nRegards,\nAiswariya.","approved":true,"created_at":"2024-02-26T12:20:23.373-05:00","updated_at":"2024-02-26T12:20:23.373-05:00","cached_votes_up":0,"cached_votes_down":0,"request_id":617,"open":true,"reply_to":{"id":702,"text":"Hi:  I have several bacterial strains that inhibit filamentous fungi; but they have not yet been tested for achieving the target yeast/mold kill over time. Is that enough work done to submit to this rfp?","approved":true,"created_at":"2024-02-24T14:24:39.292-05:00","updated_at":"2024-02-25T16:04:18.161-05:00","cached_votes_up":1,"cached_votes_down":0,"request_id":617,"open":true,"user":{"id":146253,"name":"Bruce Bleakley","role":0,"image":{"url":null,"big":{"url":null},"medium":{"url":null},"small":{"url":null}},"profile_id":"bruce-bleakley-146253","profile_info":{"id":142162,"user_id":146253,"startup_id":null,"university_id":10330,"university_start_year":null,"university_end_year":null,"title":"Principal Investigator","headline":"My research has been in soil and environmental microbiology","about":"My research has included work with pure cultures of denitrifiers, non-denitrifying N2O producers, microbes in wetlands, the genera Streptomyces and Xenorhabdus and Photorhabdus,  biological control of plant pathogenic fungi using antagonistic bacteria, and fecal coliform counts in surface 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If a competitive proposal is submitted, what is the soonest date it could be funded?","approved":true,"created_at":"2024-02-25T14:49:22.633-05:00","updated_at":"2024-02-25T16:04:48.797-05:00","cached_votes_up":1,"cached_votes_down":0,"request_id":617,"open":true,"replies":[{"id":717,"text":"Hi Gloria,\nThank you for your question. We will notify within one month after the closing of the requests for proposals if it is under consideration for funding and then set up a call to review and outline next steps with those proposals being considered. Timing of funding is dependent on contract negotiations that take place outside of the Halo platform. I hope this answers your question.\nRegards,\nAiswariya.","approved":true,"created_at":"2024-02-26T12:32:50.314-05:00","updated_at":"2024-02-26T12:32:50.314-05:00","cached_votes_up":0,"cached_votes_down":0,"request_id":617,"open":true,"reply_to":{"id":704,"text":"Could you outline the time line of this process? If a competitive proposal is submitted, what is the soonest date it could be funded?","approved":true,"created_at":"2024-02-25T14:49:22.633-05:00","updated_at":"2024-02-25T16:04:48.797-05:00","cached_votes_up":1,"cached_votes_down":0,"request_id":617,"open":true,"user":{"id":7793,"name":"Gloria Muday","role":0,"image":{"url":null,"big":{"url":null},"medium":{"url":null},"small":{"url":null}},"profile_id":"gloria-muday-7793","profile_info":{"id":7821,"user_id":7793,"startup_id":null,"university_id":1169,"university_start_year":"1991","university_end_year":"Present","title":"Principal Investigator","headline":"Crop Reproduction, Heat Stress, Redox Signaling","about":"Research focuses on how reactive oxygen species and hormone networks govern pollen performance and root/stomatal function under stress. 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