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Free in vivo testing: Unleash your molecule's potential as a crop protector
What questions do you have about this RFP?
Get them answered by the team at BASF.
Background

You’ve already done all the hard work of synthesizing your molecule. Maybe it wasn’t the blockbuster pharmaceutical you envisioned, but it still has potential!  

 

Now, we would like to partner to bring new life and impact from your chemistry. You may submit multiple compounds, and we will screen them using our computer models. If they are selected, you will receive the biological results for each compound as a potential herbicide, fungicide and insecticide, and you are free to publish the results. 

 

If there is a hit, it’s up to you to decide about follow up collaboration.  

 

Start the collaboration with us: let’s discover together if that next crop protection blockbuster is sitting in your deep freezer! 

 

Process 
  1. Submit proposal on Halo  

  2. Sign MTA agreement through DocuSign 

  3. Upload file with structures to BASF's platform 

  4. In silico evaluation & BASF decision 

  5. In vivo test of selected compound at BASF 

  6. Return of in vivo results for publication  

  7. Further collaboration

What we're looking for

We are looking for novel compounds, such as organic molecules, natural products, and fragment-like molecules, which could be subjected to screening within our research facility, with the goal of developing new crop protection products.

Solutions of interest include:
  • Small organic molecules
  • Natural products
  • Virtual compounds
  • Single chemical compounds (in a dry form)
Our must-have requirements are:
  • The minimum amount of compound we will accept is 5 mg (the standard amount is 8 mg).
  • The material shall have purity greater than 80% as determined by current state-of-the-art analysis.
Our nice-to-have's are:
  • Additional amounts of compound available for further screenings (20-100 mg) if needed.
  • Analogues compounds of submitted molecule if the parent compound turns out to be a hit in the initial screening.
What's out of scope:
  • Extracts or mixtures of compounds
  • Solutions in solvents
  • Metal-containing molecules
  • Polymers
  • Nanoparticles
  • Microorganisms
  • Toxic or explosive compounds
What we can offer you
Eligible partnership models:
Material transfer
Benefits:
Data
Biological results from the preliminary tests and results from philanthropic public health programs against human pathogens (e.g. malaria)-if selected by BASF and priori agreed with partner to test.
Expertise
Partner receive logistic support and guidance over each step of the collaboration. Possibility to develop further collaboration with BASF researchers, based on preliminary results.
Facilities and Services
Free shipping of participant's compounds to BASF. To ensure the best solution and simple procedures, we also provide you free of charge our packaging materials (vials/tubes and boxes).
Compounds and Reagents
Synthesis cost for the re-ordered compound for further in vivo tests could be reimbursed.
Reviewers
AP
Anna aleksandra Michrowska Pianowska
Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition
LJ
Lauren Junker
Technology Scout
TH
Tom Holcombe
Collaboration & Scouting NA
EI
Emir Islamovic
Innovation and Partnership Manager
KB
Kavita Bitra
Technology scout
SS
Sophia Steffens
Innovation & Scouting
Q&A with BASF

The Q&A is now closed.

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Most upvoted
Q.
Are you interested solely in solid forms or could it be a liquid form?
2
A.
Dear Ana, we are interested only in solid forms. best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
December 13, 2024
Is this response helpful?
0
0
Q.
Are novel/sustainable routes to (non-commercial) compounds with know agrochemical activity (herbicide/growth regulator) of interest?
1
A.
Dear Mark, novel routs might be interested, but unfortunately they are not in scope of this project. best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
September 18, 2024
Is this response helpful?
0
0
Q.
Are commercially available compounds eligible for this RFP?
1
A.
Dear Kostas, yes we can screen the commercially available compounds (if we they are new to us), but please note that in such case, BASF has no further obligations under the signed by you Agreement. You would still get from us the biological results of tested compounds. best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
September 19, 2024
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0
0
Q.
Non identified yet compounds in a bacterial extract inhibiting a wide range of phytopathogens, is that of interest?
1
A.
Unfortunately, we cannot accept non identified compounds.
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
October 17, 2024
Is this response helpful?
0
0
Q.
You say no nanoparticles, but what about tiny particles that are outside the regulatory definition of a nanoparticle, i.e. >100nm?, but for example of a scale 100-200nm?
1
A.
Dear Michael, Unfortunately, we are also not interested in such compounds in this program. best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
November 4, 2024
Is this response helpful?
0
0
Q.
bio-nanoinputs with antimicrobial, defense inducer and adyuvant properties, is that of interest?
1
A.
No, unfortunately it is out of the scope of this program.
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
January 6, 2025
Is this response helpful?
0
0
Q.
Are whole cell micro-organisms within the scope of your project? What bioassays are involved in your screening process? And would we maintain the right to patent successful organisms?
1
A.
Dear Emma, Unfortunately, we are not interested in whole cell micro-organisms only organic compounds are in scope of the program. best wishes, Anna
AP
Anna aleksandra Michrowska Pianowska, Leader of the Open Innovation Platform Agro and External Synthesis & Compound Acquisition, BASF
October 24, 2024
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Seeking partners focused on
Agricultural Engineering
Agricultural Science
Analytical Chemistry
Antimicrobials
Biochemistry
Biocides
Computational Chemistry
Environmental Chemistry
Food Chemistry & Biochemistry
Medicinal Chemistry
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Molecular Biology
Molecular Medicine
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